BDBM285441 N-[7-(1,5-dimethyl-6-oxopyridin-3-yl)-2- propyl-2,3-dihydro-1-benzofuran-5-yl] ethanesulfonamide::US10023592, Example 495::US10941160, Example 495

SMILES CCCC1Cc2cc(NS(=O)(=O)CC)cc(c2O1)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=PBORVZVPTRTNPQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285441   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM285441(N-[7-(1,5-dimethyl-6-oxopyridin-3-yl)-2- propyl-2,...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM285441(N-[7-(1,5-dimethyl-6-oxopyridin-3-yl)-2- propyl-2,...)
Affinity DataIC50: <500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent